Biological Markers for Alzheimer’s Disease

Neurodegenerative Biomarkers in Healthy Elderly – with special reference to the preclinical pattern of biological and cognitive markers for Alzheimer’s disease

ENGLISH Neurodegenerative Biomarkers in Healthy Elderly – with special reference to the preclinical pattern of biological and cognitive markers for Alzheimer’s disease

Evaluation of Asarum europaeum L. Rhizome for the Biological Activities Related to Alzheimer’s Disease

Background and objectives: Asarum europaeum L. is an herbal medicine belonging to the family Aristolochiaceae. The rhizome of the plant has been used for the treatment of various diseases in complementary and alternative medicine of various countries. In Iranian traditional medicine (ITM), the aqueous extract of the rhizome has been used for the improvement and enhance...

Qualification opinion of Alzheimer’s disease novel methodologies/biomarkers for PET amyloid imaging (positive/negative) as a biomarker for enrichment, for use in regulatory clinical trials in predementia Alzheimer’s disease

Survey of potential diagnostic metabolite markers in serum of the rat model of Alzheimer’s disease using nuclear magnatic resonance (1H-NMR) technique

Introduction: The high prevalence of Alzheimerchr('39')s disease (AD) in todaychr('39')s societies indicates an urgent need for the development of methods that will help the early diagnosis of the disease. In this study, using proton nuclear magnetic resonance spectrometry (1H-NMR) metabolomics, identification of altered and distinct metabolites in serum of the rat model of AD was performed com...

Alzheimer’s Disease: Diagnosis and MRI Imaging

17. Verwey NA, van der Flier WM, et al. “A worldwide multicentre comparison of assays for cerebral spinal fluid biomarkers in Alzheimer’s disease.” Ann Clin Biochem 209; 26:235-40 (E-published Apr. 2, 2009). Conclusion: While no single finding affords the diagnosis of Alzheimer’s disease, the brain MRI pattern of atrophy in the mesial and lateral temporal, isthmus cingulate, and orbitofrontal a...